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Article

Effects of isothiocyanate alkyl chain-length on hamster liver cytochrome P-450 activity.

Cancer letters - 29 Jul 1994

Hamilton S M, Zhang Z, Teel R W

Abstract excerpt

The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is metabolized by various isozymes of cytochrome P-450 present in microsomes. In this study, we examined the effects of the isothiocyanate homologues, phenyl isothiocyanate (PITC), benzyl isothiocyanate (BITC), phenethyl isothiocyanate (PEITC) and phenylpropyl isothiocyanate (PPITC) on the mutagenicity and in vitro metabolism of...

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Identifiers

PMID: 8050094
DOI: 10.1016/0304-3835(94)90015-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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