Geographical distribution of haplotypes in Swedish families with Huntington's disease.

doi:10.1007/BF00202856

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Article

Geographical distribution of haplotypes in Swedish families with Huntington's disease.

Human genetics - 1 Aug 1994

Almqvist E, Andrew S, Theilmann J, Goldberg P, Zeisler J, Drugge U, Grandell U, Tapper-Persson M, Winblad B, Hayden M

Abstract excerpt

This study was planned to determine the number of origins of the mutation underlying Huntington's disease (HD) in Sweden. Haplotypes were constructed for 23 different HD families, using six different polymorphisms [(CCG)n, GT70, 674, BS1, E2 and 4.2], including two within the gene. In addition, e...

Topics

Alleles
DNA
Genetic Markers
Haplotypes
Humans
Huntington Disease
Polymorphism, Genetic
Repetitive Sequences, Nucleic Acid
Sweden

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