Article
Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.
The EMBO journal - 1 Jan 1990
Gardiner K, Horisberger M, Kraus J, Tantravahi U, Korenberg J, Rao V, Reddy S, Patterson D
Abstract excerpt
Human chromosome 21 has been analyzed by pulsed-field gel electrophoresis using somatic cell hybrids containing limited regions of the chromosome and greater than 60 unique sequence probes. Thirty-three independent NotI fragments have been identified, totalling 43 million bp. This must account fo...
Topics
- Base Composition
- Chromosome Aberrations
- Chromosome Mapping
- Chromosomes, Human, Pair 21
- DNA Probes
- Electrophoresis
- Humans
- Hybrid Cells
- Methylation
- Nucleic Acid Hybridization
- Phenotype
- Restriction Mapping