Article
Construction of high-resolution comparative maps in mammals using BAC-end sequences.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Larkin Denis M, Lewin Harris A
Abstract excerpt
Whole-genome bacterial artificial chromosome (BAC) libraries for approximately 40 representative species of mammals provide unique resources for the construction of high-resolution ordered genomic maps, the development of species genetics, and multispecies genome comparisons. Herein we describe procedures to construct high-quality radiation hybrid comparative maps using BAC-end sequences (BESs). This approach has...
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