Article
Biology of the neoplastic lymphocyte in B-CLL.
Bailliere's clinical haematology - 1 Dec 1993
Dighiero G
Abstract excerpt
Immunological markers have identified the proliferating lymphocyte in CLL as a mature B lymphocyte which, unlike lymphocytes in other B cell malignancies, expresses low amounts of surface membrane immunoglobulin (smIg), forms rosettes with mouse erythrocytes and expresses the CD5 marker. It has b...
Topics
- Agammaglobulinemia
- Antigens, Differentiation, B-Lymphocyte
- Autoimmune Diseases
- B-Lymphocytes
- Biomarkers, Tumor
- Cell Differentiation
- Chromosome Aberrations
- Gene Expression Regulation, Leukemic
- Genes, Immunoglobulin
- Humans
- Killer Cells, Natural
- Leukemia, Lymphocytic, Chronic, B-Cell
- Neoplasm Proteins
- Neoplastic Stem Cells
- Oncogenes
- Phenotype
- Receptors, Antigen, B-Cell
- T-Lymphocyte Subsets