Article
Biology of the neoplastic lymphocyte in B-CLL.
Bailliere's clinical haematology - 1 Dec 1993
Dighiero G
Abstract excerpt
Immunological markers have identified the proliferating lymphocyte in CLL as a mature B lymphocyte which, unlike lymphocytes in other B cell malignancies, expresses low amounts of surface membrane immunoglobulin (smIg), forms rosettes with mouse erythrocytes and expresses the CD5 marker. It has been postulated that Ly1 B cells (the murine counterpart of human CD5+B cells) constitute a separate B cell lineage....
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