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Article

Complementation analysis of pseudorabies virus gE and gI mutants in retinal ganglion cell neurotropism.

Journal of virology - 1 Aug 1994

Enquist L W, Dubin J, Whealy M E, Card J P

Abstract excerpt

Pseudorabies virus glycoproteins gE and gI are required to infect some, but not all, regions of the rodent central nervous system after peripheral injection. After infection of the retina, pseudorabies virus mutants lacking either gE or gI can subsequently infect neural centers involved in the control of circadian function but cannot infect visual circuits mediating visual perception or the reflex movement of the...

Topics

Animals
Genetic Complementation Test
Herpesvirus 1, Suid
Mutation
Rats
Retinal Ganglion Cells
Viral Envelope Proteins
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8035525
DOI: 10.1128/JVI.68.8.5275-5279.1994
PMCID: PMC236473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8035525-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Complementation analysis of pseudorabies virus gE and gI mutants in retinal ganglion cell neurotropism.PMID 8035525Read ↗

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