Article
Synergy and resistance to synergy between beta-lactam antibiotics and glycopeptides against glycopeptide-resistant strains of Enterococcus faecium.
Antimicrobial agents and chemotherapy - 1 Apr 1994
Gutmann L, al-Obeid S, Billot-Klein D, Guerrier M L, Collatz E
Abstract excerpt
A synergistic effect between vancomycin or teicoplanin and different beta-lactam antibiotics was found for two strains of Enterococcus faecium, EFM4 and EFM11, expressing resistance to glycopeptides and belonging to the VANA class. The MICs of penicillin for these two strains were 16 and 128 micr...
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Carrier Proteins
- Cytoplasm
- Drug Resistance, Microbial
- Drug Synergism
- Enterococcus faecium
- Glycopeptides
- Hexosyltransferases
- Membranes
- Microbial Sensitivity Tests
- Muramoylpentapeptide Carboxypeptidase
- Mutation
- Penicillin-Binding Proteins