Article
The effect of variation in the apolipoprotein B gene on plasmid lipid and apolipoprotein B levels. I. A likelihood-based approach to cladistic analysis.
Annals of human genetics - 1 Jan 1994
Hallman D M, Visvikis S, Steinmetz J, Boerwinkle E
Abstract excerpt
A new method is described for employing family data to test for significant haplotype effects on continuously distributed variables, using likelihood-ratio tests of linear models in which haplotype effects are parameterized and familial correlations taken into account. The method is applied to th...
Topics
- Adolescent
- Adult
- Apolipoproteins B
- Base Sequence
- Child
- Female
- France
- Gene Frequency
- Genetic Variation
- Haplotypes
- Humans
- Linear Models
- Lipids
- Male
- Middle Aged
- Molecular Sequence Data
- Phylogeny
- Polymorphism, Genetic