Article
Variability within the Candida rugosa lipases family.
Protein engineering - 1 Apr 1994
Lotti M, Tramontano A, Longhi S, Fusetti F, Brocca S, Pizzi E, Alberghina L
Abstract excerpt
Several fungi secrete lipase isozymes differing in biochemical properties and in some cases in substrate specificity. In the yeast Candida rugosa, a family of related genes encodes for multiple lipase proteins, highly homologous in sequence but partially different in the regions interacting with the substrate molecule. Analysis of these substitutions performed on the basis of multiple alignments and using a 3-D...
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