Article
Loss of the Compound Action Potential: an Electrophysiological, Biochemical and Morphological Study of Early Events in Axonal Degeneration in the C57BL/Ola Mouse
1 Apr 1994
Abstract excerpt
In the C57BL/Ola (Ola) mouse strain there is a marked slowing of axonal disintegration during Wallerian degeneration. The locus of the mutation controlling this phenomenon (slow Wallerian degeneration--Wlds) has been mapped to chromosome 4, and its protective effect decreases with advancing age. Using biochemical, electrophysiological and histological techniques, the present study was undertaken to determine...
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