Article
Effects of substitution of proposed Zn(II) ligand His81 or His64 in phage T4 gene 32 protein: spectroscopic evidence for a novel zinc coordination complex.
Biochemistry - 5 Jul 1994
Qiu H, Giedroc D P
Abstract excerpt
T4 gene 32 protein (gp32), the prototype helix-destabilizing or single-stranded (ss) DNA binding protein, contains one tightly coordinated Zn2+ ion bound tetrahedrally by three cysteines (residues 77, 87, and 90) and a fourth non-thiol donor. In previous work, it was shown that the proposed non-t...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Bacteriophage T4
- Chlorine
- DNA-Binding Proteins
- Genes, Viral
- Isotopes
- Ligands
- Magnetic Resonance Spectroscopy
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Poly A
- Poly dA-dT
- Structure-Activity Relationship
- Trypsin
- Viral Proteins
- Zinc