Article
Improvement of Cd(2+) uptake ability of SmtA protein by Lys/Cys mutation; experimental and theoretical studies.
Journal of biomolecular structure & dynamics - 1 Jan 2015
Saffar B, Mehri Ghahfarrokhi A, Mahnam K, Mobini-Dehkordi M
Abstract excerpt
The improved Cd(2+) surface affinity characteristics of a mutated cyanobacterial metallothionein SmtA (K45C) were investigated via experimental and theoretical methods. Molecular dynamics simulations were carried out using a model of Cd(2+) and other ions enclosed in a fully hydrated simulation box with the wild-type or mutated SmtA protein. The theoretical results suggested that mutated SmtA was more powerful in...
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