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Article

Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals.

Science (New York, N.Y.) - 8 Jul 1994

Graziosi C, Pantaleo G, Gantt K R, Fortin J P, Demarest J F, Cohen O J, Sékaly R P, Fauci A S

Abstract excerpt

A switch from a T helper 1 (TH1) cytokine phenotype to a TH2 phenotype has been proposed as a critical element in the progression of human immunodeficiency virus (HIV) disease. Here, constitutive cytokine expression was analyzed in unfractionated and sorted cell populations isolated from peripheral blood and lymph nodes of HIV-infected individuals at different stages of disease. Expression of interleukin-2 (IL-2)...

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Source

Identifiers

PMID: 8023143
DOI: 10.1126/science.8023143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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