Article
Information and clonal concepts in ageing.
Medical hypotheses - 1 Feb 1994
Morris J A
Abstract excerpt
A model based on information theory and one based on somatic mutation in an expanding pool of cells are combined to give a theory of ageing. A mathematical formula, based on concepts from information theory, gives a close fit to the age incidence of mortality and disease in middle and old age. The basic concept is that biological systems process information and make decisions to maintain their integrity. But the...
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