Article
Inherited glutathione-S-transferase deficiency is a risk factor for pulmonary asbestosis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 1994
Smith C M, Kelsey K T, Wiencke J K, Leyden K, Levin S, Christiani D C
Abstract excerpt
Pulmonary diseases attributable to asbestos exposure constitute a significant public health burden, yet few studies have investigated potential genetic determinants of susceptibility to asbestos-related diseases. The glutathione-S-transferases are a family of conjugating enzymes that both catalyze the detoxification of a variety of potentially cytotoxic electrophilic agents and act in the generation of...
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