Article
The glutathione S-transferase theta and mu deletion polymorphisms in asbestosis.
American journal of industrial medicine - 1 Mar 1997
Kelsey K T, Nelson H H, Wiencke J K, Smith C M, Levin S
Abstract excerpt
The glutathione S-transferases (GSTs) catalyze the conjugation of a wide variety of reactive, electrophilic substrates with glutathione, facilitating their excretion. There is also evidence that GSTs can catalyze glutathione conjugation of lipid radicals as well as act in the generation of leukotriene inflammatory mediators. Studying construction carpenters screened for the presence of asbestos-related diseases,...
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