Article
Initiation of recombination in Saccharomyces cerevisiae haploid meiosis.
Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 1994
De Massy B, Baudat F, Nicolas A
Abstract excerpt
In most eukaryotes during prophase I of meiosis, homologous chromosomes pair and recombine by coordinated molecular and cellular processes. To directly test whether or not the early steps of the initiation of recombination depend on the presence of a homologous chromosome, we have examined the formation and processing of DNA double-strand breaks (DSBs, the earliest physical landmark of recombination initiation)...
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