Article
Molecular biology of Beckwith-Wiedemann syndrome.
Medical and pediatric oncology - 1 Nov 1996
Weksberg R, Squire J A
Abstract excerpt
Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome associated with a predisposition to embryonal tumors, most commonly Wilms' (WT). Overlapping clinical phenotypes are seen in two other disorders, Simpson-Golabi-Behmel syndrome (SGBS) and Perlman syndrome (PS). BWS is a genetically heter...
Topics
- Beckwith-Wiedemann Syndrome
- Chromatin
- Chromosomes, Human, Pair 11
- DNA Replication
- Gene Expression Regulation, Neoplastic
- Genes, Dominant
- Genomic Imprinting
- Humans
- Insulin-Like Growth Factor II
- Models, Genetic
- Molecular Biology
- Neoplasms, Germ Cell and Embryonal
- Phenotype
- Syndrome
- Translocation, Genetic
- Wilms Tumor