Genetic factors in type 2 diabetes: the end of the beginning?

doi:10.1126/science.1104346

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Article

Genetic factors in type 2 diabetes: the end of the beginning?

Science (New York, N.Y.) - 21 Jan 2005

O'Rahilly Stephen, Barroso Inês, Wareham Nicholas J

Abstract excerpt

The intensive search for genetic variants that predispose to type 2 diabetes was launched with optimism, but progress has been slower than was hoped. Even so, major advances have been made in the understanding of monogenic forms of the disease which together represent a substantial health burden, and a few common gene variants that influence susceptibility have now been unequivocally identified. Armed with a...

Topics

Animals
Diabetes Mellitus, Type 2
Disease Models, Animal
Genetic Predisposition to Disease
Genetic Techniques
Genetic Variation
Humans
Life Style
Multifactorial Inheritance
Mutation
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 15662000
DOI: 10.1126/science.1104346

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