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Article

A large Swedish family with Alzheimer's disease with a codon 670/671 amyloid precursor protein mutation. A clinical and genealogical investigation.

Archives of neurology - 1 Dec 1994

Axelman K, Basun H, Winblad B, Lannfelt L

Abstract excerpt

OBJECTIVE: To describe clinical and genealogic features in a Swedish family with Alzheimer's disease with a double mutation of the amyloid precursor protein gene at codon 670/671 and to study the effects of anticipation and imprinting. DESIGN: Interviews with relatives, clinical investigations of...

Topics

Adult
Alzheimer Disease
Amyloid beta-Protein Precursor
Codon
Genes
Humans
Middle Aged
Mutation
Pedigree
Sweden

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7986173
DOI: 10.1001/archneur.1994.00540240037013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7986173-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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