Article
The polymerase chain reaction detects B cell clonalities in patients with Sjögren's syndrome and suspected malignant lymphoma.
The Journal of rheumatology - 1 Aug 1994
De Vita S, Ferraccioli G, De Re V, Dolcetti R, Carbone A, Bartoli E, Boiocchi M
Abstract excerpt
OBJECTIVE: To investigate the usefulness of the polymerase chain reaction (PCR) to detect B cell clonal expansions in tissues where lymphoproliferative disease was suspected in the course of Sjögren's syndrome (SS). METHODS: Tissue samples from 7 patients with definite (5 cases) or probable (2 cases) SS were subjected to routine histopathologic studies, immunophenotyping, and genotypic analysis, including...
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