Article
Identification of T cell autoepitopes that cross-react with the C-terminal segment of the M protein of group A streptococci
1 Jan 1994
Abstract excerpt
Rheumatic fever (RF) follows a throat infection with different M-serotypes of beta-hemolytic group A streptococci (GAS) and can affect different tissues, predominantly the heart. It is thought to be an autoimmune illness. Although histological examination of affected heart shows an infiltrate consisting mainly of T cells, antigens or epitopes that could be putative targets of autoimmune T cells have not been...
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