Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of Disease

19 Aug 2014

Abstract excerpt

RATIONALE: Molecular mimicry theory (MMT) suggests that epitope mimicry between pathogens and human proteins can activate autoimmune disease. Group A streptococci (GAS) mimics human cardiac myosin in rheumatic heart disease (RHD) and coxsackie viruses (CX) mimic actin in autoimmune myocarditis (AM). But myosin and actin are immunologically inaccessible and unlikely initial targets. Extracellular cardiac proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammatory Myopathies and Dermatomyositis
Share to Streptococcal Infections and Treatments
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25191648
DOI: 10.3389/fped.2014.00085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of DiseasePMID 25191648Read ↗

Molecular mimicry in the autoimmune pathogenesis of rheumatic heart diseaseSemantic proximity Read ↗

Rheumatic heart disease: mediation by complex immune events.Semantic proximity Read ↗

Molecular pathogenesis of rheumatic fever and rheumatic heart diseaseSemantic proximity Read ↗

Myosin 16 mimicries may explain post- COVID-19 related neurological consequencesSemantic proximity Read ↗

T Cell Mimicry and Epitope Specificity of Cross-Reactive T Cell Clones from Rheumatic Heart DiseaseSemantic proximity Read ↗

Rheumatic fever and rheumatic heart disease: cellular mechanisms leading autoimmune reactivity and disease.Semantic proximity Read ↗

Molecular Mimicry: Its Evolution from Concept to Mechanism as a Cause of Autoimmune DiseasesSemantic proximity Read ↗

An immunological perspective on rheumatic heart disease pathogenesis: more questions than answers.Semantic proximity Read ↗

The role of molecular mimicry and other factors in the association of Human Endogenous Retroviruses and autoimmunitySemantic proximity Read ↗

Molecular mimicry and immune-mediated diseases.Semantic proximity Read ↗

Molecular mimicry: An explanation for autoimmune diseases and infertilitySemantic proximity Read ↗

Molecular Mimicry and UveitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.