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Article

Effect of IGF‐I on pig oocyte maturation, fertilization, and early embryonic development in vitro, and on granulosa and cumulus cell biosynthetic activity

1 Aug 1994

Abstract excerpt

Abstract Porcine granulosa cells have been shown previously to both secrete and respond to insulin‐like growth factor‐I (IGF‐I), suggesting an autocrine function of this peptide in the follicle. The present work was undertaken to determine possible effects of IGF‐I on in vitro maturation, in vitro fertilization, and early embryonic development in culture. Granulosa and cumulus cell proliferation and...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 7980945
DOI: 10.1002/mrd.1080380404

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