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Insulin-Like Growth Factors and Ovarian Follicular Development*

1 Nov 1992

Abstract excerpt

INSULIN-like growth factor-I (IGF-I) and its structural homologue, IGF-II, are low molecular weight peptides that promote cellular mitosis and differentiation in a variety of systems and are believed to play a role in cyclic ovarian follicular development. In 1978, IGF-I and IGF-II were purified and sequenced by Rinderkneckt and Humbel (1, 2), and since that time there has been an exponential accumulation of...

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Identifiers

PMID: 1281087
DOI: 10.1210/edrv-13-4-641

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Source receipt: pubmed, retrieved 7 Sept 2026.

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