Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.

doi:10.1006/bbrc.1994.2598

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.

Biochemical and biophysical research communications - 15 Nov 1994

Horii A, Han H J, Sasaki S, Shimada M, Nakamura Y

Abstract excerpt

Mutations in genes associated with the DNA mismatch repair system were considered to play important roles in predisposition to cancer, since hMSH2 and hMLH1, human homologues of yeast MSH2 and MLH1 as well as bacterial mutS and mutL genes, were found to be involved in hereditary nonpolyposis colo...

Topics

Amino Acid Sequence
Base Sequence
Brain
Carrier Proteins
Chromosome Mapping
Chromosomes, Human, Pair 7
Cloning, Molecular
DNA
DNA Primers
DNA Repair
Fetus
Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Library

Genes, Bacterial

Genes, Fungal

Genetic Predisposition to Disease

Humans

In Situ Hybridization, Fluorescence

Source

Open in PubMed

Identifiers

PMID: 7980603
DOI: 10.1006/bbrc.1994.2598

Genes

PMS1
MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7980603-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.PMID 7980603Read ↗

MutS Homologues hMSH4 and hMSH5: Genetic Variations, Functions, and Implications in Human DiseasesSemantic proximity Read ↗

MutS homologues hMSH4 and hMSH5: diverse functional implications in humans.Semantic proximity Read ↗

Genomic Organization of the HumanPMS2Gene FamilySemantic proximity Read ↗

Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations.Semantic proximity Read ↗

Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC)Semantic proximity Read ↗

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.Semantic proximity Read ↗

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.Semantic proximity Read ↗

MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in YeastSemantic proximity Read ↗

Isolation and characterization of the 5' region of the human mismatch repair gene hPMS1.Semantic proximity Read ↗

Assessing pathogenicity of MLH1 variants by co-expression of human MLH1 and PMS2 genes in yeast.Semantic proximity Read ↗

Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damageSemantic proximity Read ↗

Cloning and Expression Analysis of a Meiosis-Specific MutS Homolog: The HumanMSH4GeneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.