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Article

Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas

1 Nov 1994

Abstract excerpt

BACKGROUND: Cancer is caused by the accumulation of mutations that activate proto-oncogenes and inactivate tumor suppressor genes. The result is a clonal expansion of genetically identical daughter cells that eventually become clinical malignancies. The specific mutations acquired by the progenitor cell are like a fingerprint carried by each cell of the tumor. These mutations can serve as very specific markers...

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Share to Head and Neck Cancer Studies
Share to Salivary Gland Disorders and Functions
Share to Salivary Gland Tumors Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 7977967
DOI: 10.1016/s0002-9610(05)80092-3

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