Clonal divergence in Escherichia coli as a result of recombination, not mutation.

doi:10.1126/science.7973728

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Article

Clonal divergence in Escherichia coli as a result of recombination, not mutation.

Science (New York, N.Y.) - 25 Nov 1994

Guttman D S, Dykhuizen D E

Abstract excerpt

Nucleotide sequence analysis was performed on 12 natural isolates of Escherichia coli in four loci located in close proximity on the chromosome. A comparison of gene genealogies indicated that three recombination events have occurred in a subset of the strains (ECOR group A) in the time since the...

Topics

Biological Evolution
Carbon-Nitrogen Ligases
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Glucosephosphate Dehydrogenase
Molecular Sequence Data
Mutation
Peptide Hydrolases
Phylogeny
Recombination, Genetic
Sequence Analysis, DNA
Transaminases

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