Article
The relative contributions of recombination and point mutation to the diversification of bacterial clones.
Current opinion in microbiology - 1 Oct 2001
Spratt B G, Hanage W P, Feil E J
Abstract excerpt
Low levels of recombination in bacterial species have often been inferred from the presence of linkage disequilibrium between the alleles at different loci in the population. However, significant linkage disequilibrium is inevitable in organisms that divide by binary fission, and recombinational replacements must be very frequent, compared to point mutation, to dissipate disequilibrium. Recent studies using data...
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