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High Recombinant Frequency in Extraintestinal Pathogenic<i>Escherichia coli</i>Strains

24 Mar 2015

Abstract excerpt

Homologous recombination promotes genetic diversity by facilitating the integration of foreign DNA and intrachromosomal gene shuffling. It has been hypothesized that if recombination is variable among strains, selection should favor higher recombination rates among pathogens, as they face additional selection pressures from host defenses. To test this hypothesis we have developed a plasmid-based method for...

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PMID: 25804522
DOI: 10.1093/molbev/msv072

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