Article
Role of homologous recombination in adaptive diversification of extraintestinal Escherichia coli.
Journal of bacteriology - 1 Jan 2013
Paul Sandip, Linardopoulou Elena V, Billig Mariya, Tchesnokova Veronika, Price Lance B, Johnson James R, Chattopadhyay Sujay, Sokurenko Evgeni V
Abstract excerpt
The contribution of homologous exchange (recombination) of core genes in the adaptive evolution of bacterial pathogens is not well understood. To investigate this, we analyzed fully assembled genomes of two Escherichia coli strains from sequence type 131 (ST131), a clonal group that is both the leading cause of extraintestinal E. coli infections and the main source of fluoroquinolone-resistant E. coli. Although...
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