Signals on proteins, intracellular targeting and inborn errors of organellar metabolism.

doi:10.1007/BF00711361

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Article

Signals on proteins, intracellular targeting and inborn errors of organellar metabolism.

Journal of inherited metabolic disease - 1 Jan 1994

Tager J M, Aerts J M, van den Bogert C, Wanders R J

Abstract excerpt

Newly synthesized polypeptides contain signals that direct them to the appropriate intracellular organelles and the organelles contain receptors that recognize the signals. Protein synthesis occurs either on free ribosomes or on ribosomes bound to the endoplasmic reticulum. The proteins synthesiz...

Topics

Biological Transport
Humans
Lysosomes
Metabolism, Inborn Errors
Microbodies
Mitochondria
Mutation
Proteins
Signal Transduction

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