Article
The characterisation of p53 binding phage isolated from phage peptide display libraries.
Journal of molecular biology - 4 Nov 1994
Daniels D A, Lane D P
Abstract excerpt
Peptide phage display libraries were screened for peptides that bind to the tumour suppressor protein, human p53. Three p53 binding peptides were isolated respectively from hexamer (6-mer), dodecamer (12-mer) and icosomer (20-mer) libraries. We have characterised their interaction with p53 in detail. The phage appear to bind regions on native p53 common between mouse and man. Two conformation-specific anti-p53...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
