Article
Identification and characterization of a suite of tumor targeting peptides for non-small cell lung cancer.
Scientific reports - 27 Mar 2014
McGuire Michael J, Gray Bethany Powell, Li Shunzi, Cupka Dorothy, Byers Lauren Averett, Wu Lei, Rezaie Shaghayegh, Liu Ying-Horng, Pattisapu Naveen, Issac James, Oyama Tsukasa, Diao Lixia, Heymach John V, Xie Xian-Jin, Minna John D, Brown Kathlynn C
Abstract excerpt
Tumor targeting ligands are emerging components in cancer therapies. Widespread use of targeted therapies and molecular imaging is dependent on increasing the number of high affinity, tumor-specific ligands. Towards this goal, we biopanned three phage-displayed peptide libraries on a series of well-defined human non-small cell lung cancer (NSCLC) cell lines, isolating 11 novel peptides. The peptides show distinct...
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