Article
Further studies on the relationship between dopamine cell density and haloperidol-induced catalepsy.
The Journal of pharmacology and experimental therapeutics - 1 Nov 1994
Hitzemann B, Dains K, Kanes S, Hitzemann R
Abstract excerpt
Previous data have suggested that the genetic variability in the sensitivity to haloperidol-induced catalepsy is associated with the number of dopamine neurons in the substantia nigra zona compacta (SNZc). To further investigate this relationship, neuroleptic responsive (NR) and neuroleptic nonresponsive (NNR) lines were selected from the new heterogeneous stock/Northport (Np). At the fourth selected generation...
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