Article
Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg-dependent protein phosphatase.
The Journal of biological chemistry - 18 Nov 1994
Park I K, DePaoli-Roach A A
Abstract excerpt
Inhibitor-2 (I-2) inhibits the free catalytic subunit of type 1 phosphatase (CS1) and controls the cyclic inactivation/activation of CS1 in the ATP-Mg-dependent protein phosphatase complex. We report here the effect of mutations on these two properties of I-2. Substitution of Thr-72 with Ala, Asp...
Topics
- Adenosine Triphosphate
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- Casein Kinase II
- Glycogen Synthase Kinase 3
- Glycogen Synthase Kinases
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Phosphoprotein Phosphatases
- Phosphorylation
- Proline
- Protein Serine-Threonine Kinases
- Proteins
- Rabbits