Article
sxy-1, a Haemophilus influenzae mutation causing greatly enhanced spontaneous competence.
Journal of bacteriology - 1 Sept 1991
Redfield R J
Abstract excerpt
A Haemophilus influenzae strain carrying a competence-enhancing mutation (sxy-1) was selected by transformation of a mutagenized culture in exponential growth at low cell density, where spontaneous competence is very rare. Under these conditions, sxy-1 cells spontaneously transformed 100 to 1,000 times more efficiently than wild-type cells. Moreover, sxy-1 cells responded to all known competence-inducing...
Topics
- Anaerobiosis
- Cyclic AMP
- DNA, Bacterial
- Genes, Bacterial
- Haemophilus influenzae
- Mutation
- Phenotype
- Recombination, Genetic
- Transformation, Genetic