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Article

Mutational analysis of Glu771 of the Ca(2+)-ATPase of sarcoplasmic reticulum. Effect of positive charge on dephosphorylation.

FEBS letters - 31 Oct 1994

Andersen J P

Abstract excerpt

The glutamic acid residue Glu771 in the fifth transmembrane segment M5 of the Ca(2+)-ATPase of rabbit fast twitch muscle sarcoplasmic reticulum was substituted with lysine, alanine, and glycine by site-directed mutagenesis. Mutant Glu771-->Lys was unable to occlude Ca2+, and Ca2+ did not inhibit phosphorylation from P(i) or activate phosphorylation from ATP of this mutant. Mutants Glu771-->Ala and Glu771-->Gly...

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PMID: 7957909
DOI: 10.1016/0014-5793(94)01100-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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