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Article

Mutational analysis of Glu771 of the Ca(2+)-ATPase of sarcoplasmic reticulum. Effect of positive charge on dephosphorylation.

FEBS letters - 31 Oct 1994

Andersen J P

Abstract excerpt

The glutamic acid residue Glu771 in the fifth transmembrane segment M5 of the Ca(2+)-ATPase of rabbit fast twitch muscle sarcoplasmic reticulum was substituted with lysine, alanine, and glycine by site-directed mutagenesis. Mutant Glu771-->Lys was unable to occlude Ca2+, and Ca2+ did not inhibit...

Topics

Animals
Binding Sites
Calcium-Transporting ATPases
Cell Line
Glutamic Acid
Microsomes
Muscle Fibers, Fast-Twitch
Mutagenesis, Site-Directed
Mutation
Phosphorylation
Protons
Rabbits

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sarcoplasmic Reticulum

Transfection

Source

Identifiers

PMID: 7957909
DOI: 10.1016/0014-5793(94)01100-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7957909-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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