Article
Mouse 3T3 fibroblasts induce rat basophilic leukemia (RBL-2H3) cells to acquire responsiveness to compound 48/80.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 1993
Swieter M, Midura R J, Nishikata H, Oliver C, Berenstein E H, Mergenhagen S E, Hascall V C, Siraganian R P
Abstract excerpt
2H3 subline of rat basophilic leukemia (RBL-2H3) cells are mast cell analogs that lack responsiveness to nonimmunologic stimuli such as compound 48/80 and substance P. To determine if fibroblasts can influence this responsiveness, RBL-2H3 cells were cocultured with confluent monolayers of mouse 3...
Topics
- 3T3 Cells
- Animals
- Cell Communication
- Fibroblasts
- Hematopoietic Cell Growth Factors
- Histamine
- Histamine Release
- Leukemia, Basophilic, Acute
- Mice
- Phenotype
- Rats
- Stem Cell Factor
- Tumor Cells, Cultured
- p-Methoxy-N-methylphenethylamine