Article
Analysis of urinary and biliary metabolites of (+)-4-[4-(4-methylphenyl)phenylmethoxy-1-piperidinyl]butyric acid in rats by liquid chromatography-frit-fast atom bombardment mass spectrometry.
Journal of chromatography. B, Biomedical applications - 5 Aug 1994
Takahara E, Nagata O, Kato H, Ohta S, Hirobe M
Abstract excerpt
The urinary and biliary metabolites of (+)-4-[4-(4-methylphenyl)phenylmethoxy-1-piperidinyl]butyric acid [(+)-MPPB] were examined in rapid-metabolizing (RM) and slow-metabolizing (SM) male Sprague-Dawley rats by means of liquid chromatography-frit-fast atom bombardment mass spectrometry. In the R...
Topics
- Animals
- Benzhydryl Compounds
- Bile
- Chromatography, Liquid
- Male
- Microsomes, Liver
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Spectrometry, Mass, Fast Atom Bombardment