Article
Xenobiotic metabolomics: major impact on the metabolome.
Annual review of pharmacology and toxicology - 1 Jan 2012
Johnson Caroline H, Patterson Andrew D, Idle Jeffrey R, Gonzalez Frank J
Abstract excerpt
Xenobiotics are encountered by humans on a daily basis and include drugs, environmental pollutants, cosmetics, and even components of the diet. These chemicals undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause unintended effects such as toxicity. They can also block the action of enzymes or receptors used for endogenous metabolism or affect the efficacy...
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