Article
Lymphocyte predominance Hodgkin's disease: lineage and clonality determination using a single-cell assay.
Blood - 15 Nov 1994
Delabie J, Tierens A, Wu G, Weisenburger D D, Chan W C
Abstract excerpt
Lymphocyte predominance Hodgkin's disease (LPHD) is a clinically indolent condition. Although there is evidence that the putative neoplastic cell in this disease, the "L&H" cell, is of B-cell lineage, there is conflicting data concerning the clonality of these cells. Our study was aimed at clarif...
Topics
- Antigens, CD
- B-Lymphocytes
- Base Sequence
- Blotting, Southern
- DNA Primers
- DNA, Neoplasm
- Genotype
- Hodgkin Disease
- Humans
- Immunoglobulin Heavy Chains
- Immunophenotyping
- Lymphocytes
