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Lymphocyte predominance Hodgkin's disease: lineage and clonality determination using a single-cell assay.

Blood - 15 Nov 1994

Delabie J, Tierens A, Wu G, Weisenburger D D, Chan W C

Abstract excerpt

Lymphocyte predominance Hodgkin's disease (LPHD) is a clinically indolent condition. Although there is evidence that the putative neoplastic cell in this disease, the "L&H" cell, is of B-cell lineage, there is conflicting data concerning the clonality of these cells. Our study was aimed at clarifying the issue of lineage and clonality of the L&H cells of LPHD using a single-cell assay. Four cases of LPHD were...

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PMID: 7949084

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