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Article

Formation of functional cross-species heterodimers of ornithine decarboxylase.

Biochemistry - 22 Nov 1994

Osterman A, Grishin N V, Kinch L N, Phillips M A

Abstract excerpt

The two active sites in ornithine decarboxylase (ODC) are formed at the dimer interface with Lys-69 and Cys-360 contributing to each active site from opposite monomers [Tobias, K. E., & Kahana, C. (1993) Biochemistry 32, 5842-5847]. To gain insight into the organization of the substrate binding site and the nature of the dimer interface, analysis of ornithine decarboxylase from two parasitic protozoa, Trypanosoma...

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PMID: 7947774
DOI: 10.1021/bi00250a016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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