Article
[Analysis of the dopamine D2 receptor gene].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology - 1 Jun 1994
Arinami T, Itokawa M
Abstract excerpt
The methods, such as Southern blot hybridization, PCR-direct sequencing and PCR-SSCP, to detect sequence variants in the human dopamine D2 receptor (DRD2) gene were described. To study the association of a missense variant of the DRD2 gene resulting in Ser311-->Cys, which was detected by PCR-direct sequencing in schizophrenics, the genotypes of controls and schizophrenics were determined by the methods of PCR-dot...
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