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Article

The topoisomerase I gene from Ustilago maydis: sequence, disruption and mutant phenotype.

Nucleic acids research - 11 Sept 1994

Gerhold D, Thiyagarajan M, Kmiec E B

Abstract excerpt

The Ustilago maydis genomic TOP1 gene encoding DNA topoisomerase I was cloned by amplifying a gene fragment using the polymerase chain reaction, and using this fragment to search a genomic DNA library by hybridization. The predicted peptide sequence exhibited 30-40% identity to other eukaryotic TOP1 genes, yet differed in several features. First, an unusually long acidic region was identified near the amino...

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Identifiers

PMID: 7937091
DOI: 10.1093/nar/22.18.3773
PMCID: PMC308361

Genes

TOP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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