Insulin-promoter-factor 1 is required for pancreas development in mice.

doi:10.1038/371606a0

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Article

Insulin-promoter-factor 1 is required for pancreas development in mice.

Nature - 13 Oct 1994

Jonsson J, Carlsson L, Edlund T, Edlund H

Abstract excerpt

The mammalian pancreas is a mixed exocrine and endocrine gland that, in most species, arises from ventral and dorsal buds which subsequently merge to form the pancreas. In both mouse and rat the first histological sign of morphogenesis of the dorsal pancreas is a dorsal evagination of the duodenu...

Topics

Animals
Cell Line
Cloning, Molecular
Female
Gene Targeting
Homeodomain Proteins
Mice
Mice, Inbred C57BL
Mutation
Pancreas
Trans-Activators

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