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Article

Insulin-promoter-factor 1 is required for pancreas development in mice.

Nature - 13 Oct 1994

Jonsson J, Carlsson L, Edlund T, Edlund H

Abstract excerpt

The mammalian pancreas is a mixed exocrine and endocrine gland that, in most species, arises from ventral and dorsal buds which subsequently merge to form the pancreas. In both mouse and rat the first histological sign of morphogenesis of the dorsal pancreas is a dorsal evagination of the duodenum at the level of the liver at around the 22-25-somite stage, and shortly thereafter a ventral evagination appears as a...

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PMID: 7935793
DOI: 10.1038/371606a0

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