Article
Mediation of Trypanosoma cruzi invasion by heparan sulfate receptors on host cells and penetrin counter-receptors on the trypanosomes.
Molecular and biochemical parasitology - 1 May 1994
Herrera E M, Ming M, Ortega-Barria E, Pereira M E
Abstract excerpt
Trypanosoma cruzi attaches and invades a large variety of mammalian cells by receptor-mediated interactions, one of them involving the binding of parasite trans-sialidase to host sialyl receptors. Three proteoglycan-deficient mutants of Chinese hamster ovary (CHO) cells were used to probe the rol...
Topics
- Animals
- CHO Cells
- Cell Adhesion
- Cricetinae
- Glycoproteins
- Glycosaminoglycans
- Hemagglutination
- Heparin
- Heparitin Sulfate
- Mutation
- Neuraminidase
- Protozoan Proteins
- Receptors, Cell Surface
- Sialic Acids
- Trypanosoma cruzi