Mutations in the cytoplasmic tail of herpes simplex virus glycoprotein H suppress cell fusion by a syncytial strain.

doi:10.1128/JVI.68.11.6985-6993.1994

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Article

Mutations in the cytoplasmic tail of herpes simplex virus glycoprotein H suppress cell fusion by a syncytial strain.

Journal of virology - 1 Nov 1994

Wilson D W, Davis-Poynter N, Minson A C

Abstract excerpt

We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate infectious progeny virions and form a s...

Topics

Alanine
Amino Acid Sequence
Animals
Base Sequence
Chlorocebus aethiops
Genetic Complementation Test
Herpesvirus 1, Human
Molecular Sequence Data
Mutation
Structure-Activity Relationship
Vero Cells
Viral Envelope Proteins

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