Low-affinity E2-binding site mediates downmodulation of E2 transactivation of the human papillomavirus type 8 late promoter.

doi:10.1128/JVI.68.11.6959-6966.1994

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Article

Low-affinity E2-binding site mediates downmodulation of E2 transactivation of the human papillomavirus type 8 late promoter.

Journal of virology - 1 Nov 1994

Stubenrauch F, Pfister H

Abstract excerpt

The constitutively active promoter P7535 of the epidermodysplasia verruciformis-associated human papillomavirus type 8 (HPV8) is transactivated by the viral E2 protein. The distribution of potential E2-binding sites (ACCN6GGT) in the viral transcription control region is highly conserved among ep...

Topics

Base Sequence
Binding Sites
Down-Regulation
Female
Humans
Molecular Sequence Data
Mutation
Oncogene Proteins, Viral
Papillomaviridae
Promoter Regions, Genetic
Transcriptional Activation
Tumor Cells, Cultured

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