Development of papillary renal cell tumours is associated with loss of Y-chromosome-specific DNA sequences.

doi:10.1002/path.1711730107

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Article

Development of papillary renal cell tumours is associated with loss of Y-chromosome-specific DNA sequences.

The Journal of pathology - 1 May 1994

Kovacs G, Tory K, Kovacs A

Abstract excerpt

Twenty-two papillary renal cell tumours were analysed by Southern hybridization using eight DNA probes from homologous regions of the X and Y chromosomes and two Y-chromosome-specific DNA probes. Sixteen of the 19 papillary renal cell tumours of male patients showed the loss of Y-chromosome-speci...

Topics

Alleles
Base Sequence
Blotting, Southern
Carcinoma, Renal Cell
DNA Probes
Female
Humans
Kidney Neoplasms
Male
Polymorphism, Restriction Fragment Length
Sequence Deletion
Y Chromosome

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